[{"@context":"http:\/\/schema.org\/","@type":"BlogPosting","@id":"https:\/\/wiki.edu.vn\/jp\/wiki3\/archives\/7946#BlogPosting","mainEntityOfPage":"https:\/\/wiki.edu.vn\/jp\/wiki3\/archives\/7946","headline":"\u03b2-\u30e9\u30af\u30bf\u30de\u30fc\u30bc – Wikipedia","name":"\u03b2-\u30e9\u30af\u30bf\u30de\u30fc\u30bc – Wikipedia","description":"\u03b2-\u30e9\u30af\u30bf\u30de\u30fc\u30bc\uff08\u30d9\u30fc\u30bf\u30e9\u30af\u30bf\u30de\u30fc\u30bc\u3001\u03b2-lactamase\uff09\u3068\u306f\u03b2\u2010\u30e9\u30af\u30bf\u30e0\u7cfb\u6297\u751f\u7269\u8cea\u3092\u52a0\u6c34\u5206\u89e3\u3059\u308b\u9175\u7d20\u3067\u3042\u308b\u3002\u30da\u30cb\u30b7\u30ea\u30f3\/\u30bb\u30d5\u30a1\u30ed\u30b9\u30dd\u30ea\u30f3\u30a2\u30df\u30c9-\u03b2-\u30e9\u30af\u30bf\u30e0\u30d2\u30c9\u30ed\u30e9\u30fc\u30bc (penicillin\uff0fcepharosporin amido-\u03b2-lactam hydrolase)\u3068\u3082\u547c\u3070\u308c\u308b\u3002EC3.5.2.6\u306b\u5206\u985e\u3055\u308c\u308b\u9175\u7d20\u3067\u3042\u308b\u3002 \u5e7e\u3064\u304b\u306e\u7a2e\u985e\u306e\u30b0\u30e9\u30e0\u9670\u6027\u83cc\u304c\u03b2-\u30e9\u30af\u30bf\u30de\u30fc\u30bc\u3092\u7523\u751f\u3059\u308b\u3053\u3068\u3067\u03b2-\u30e9\u30af\u30bf\u30e0\u306b\u5bfe\u3057\u3066\u8010\u6027\u3092\u793a\u3059\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u308b\u3002\u306a\u304a\u3001\u03b2-\u30e9\u30af\u30bf\u30e0\u8010\u6027\u306f\u03b2-\u30e9\u30af\u30bf\u30de\u30fc\u30bc\u306e\u307f\u304c\u539f\u56e0\u3067\u306f\u306a\u304fMRSA\u306e\u3088\u3046\u306b\u30da\u30cb\u30b7\u30ea\u30f3\u7d50\u5408\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u57fa\u8cea\u7279\u7570\u6027\u304c\u5909\u5316\u3057\u3066\u3082\u73fe\u308c\u308b\u3002 \u73fe\u5728\u03b2-\u30e9\u30af\u30bf\u30de\u30fc\u30bc\u306f\u57fa\u8cea\u7279\u7570\u6027\u306e\u9055\u3044\u306b\u3088\u308a \u30da\u30cb\u30b7\u30ea\u30ca\u30fc\u30bc (\u30af\u30e9\u30b9A \u03b2-\u30e9\u30af\u30bf\u30de\u30fc\u30bc) \u30e1\u30bf\u30ed-\u03b2-\u30e9\u30af\u30bf\u30de\u30fc\u30bc (\u30af\u30e9\u30b9B \u03b2-\u30e9\u30af\u30bf\u30de\u30fc\u30bc\u3001\u4e9c\u925b-\u03b2-\u30e9\u30af\u30bf\u30de\u30fc\u30bc\u3001\u30ab\u30eb\u30d0\u30da\u30cd\u30de\u30fc\u30bc) \u30bb\u30d5\u30a1\u30ed\u30b9\u30dd\u30ea\u30ca\u30fc\u30bc (\u30af\u30e9\u30b9C \u03b2-\u30e9\u30af\u30bf\u30de\u30fc\u30bc) \u30aa\u30ad\u30b5\u30b7\u30ea\u30ca\u30fc\u30bc (\u30af\u30e9\u30b9D \u03b2-\u30e9\u30af\u30bf\u30de\u30fc\u30bc) \u304c\u5b58\u5728\u3059\u308b[1][2][3][4]\u3002 \u3053\u308c\u30894\u7a2e\u306e\u03b2-\u30e9\u30af\u30bf\u30de\u30fc\u30bc\u306e\u3046\u3061\u3001\u30af\u30e9\u30b9B","datePublished":"2019-11-01","dateModified":"2019-11-01","author":{"@type":"Person","@id":"https:\/\/wiki.edu.vn\/jp\/wiki3\/archives\/author\/lordneo#Person","name":"lordneo","url":"https:\/\/wiki.edu.vn\/jp\/wiki3\/archives\/author\/lordneo","image":{"@type":"ImageObject","@id":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","height":96,"width":96}},"publisher":{"@type":"Organization","name":"Enzyklop\u00e4die","logo":{"@type":"ImageObject","@id":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","url":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","width":600,"height":60}},"image":{"@type":"ImageObject","@id":"https:\/\/ja.wikipedia.org\/wiki\/Special:CentralAutoLogin\/start?type=1x1","url":"https:\/\/ja.wikipedia.org\/wiki\/Special:CentralAutoLogin\/start?type=1x1","height":"1","width":"1"},"url":"https:\/\/wiki.edu.vn\/jp\/wiki3\/archives\/7946","about":["Wiki"],"wordCount":356,"articleBody":"\u03b2-\u30e9\u30af\u30bf\u30de\u30fc\u30bc\uff08\u30d9\u30fc\u30bf\u30e9\u30af\u30bf\u30de\u30fc\u30bc\u3001\u03b2-lactamase\uff09\u3068\u306f\u03b2\u2010\u30e9\u30af\u30bf\u30e0\u7cfb\u6297\u751f\u7269\u8cea\u3092\u52a0\u6c34\u5206\u89e3\u3059\u308b\u9175\u7d20\u3067\u3042\u308b\u3002\u30da\u30cb\u30b7\u30ea\u30f3\/\u30bb\u30d5\u30a1\u30ed\u30b9\u30dd\u30ea\u30f3\u30a2\u30df\u30c9-\u03b2-\u30e9\u30af\u30bf\u30e0\u30d2\u30c9\u30ed\u30e9\u30fc\u30bc (penicillin\uff0fcepharosporin amido-\u03b2-lactam hydrolase)\u3068\u3082\u547c\u3070\u308c\u308b\u3002EC3.5.2.6\u306b\u5206\u985e\u3055\u308c\u308b\u9175\u7d20\u3067\u3042\u308b\u3002\u5e7e\u3064\u304b\u306e\u7a2e\u985e\u306e\u30b0\u30e9\u30e0\u9670\u6027\u83cc\u304c\u03b2-\u30e9\u30af\u30bf\u30de\u30fc\u30bc\u3092\u7523\u751f\u3059\u308b\u3053\u3068\u3067\u03b2-\u30e9\u30af\u30bf\u30e0\u306b\u5bfe\u3057\u3066\u8010\u6027\u3092\u793a\u3059\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u308b\u3002\u306a\u304a\u3001\u03b2-\u30e9\u30af\u30bf\u30e0\u8010\u6027\u306f\u03b2-\u30e9\u30af\u30bf\u30de\u30fc\u30bc\u306e\u307f\u304c\u539f\u56e0\u3067\u306f\u306a\u304fMRSA\u306e\u3088\u3046\u306b\u30da\u30cb\u30b7\u30ea\u30f3\u7d50\u5408\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u57fa\u8cea\u7279\u7570\u6027\u304c\u5909\u5316\u3057\u3066\u3082\u73fe\u308c\u308b\u3002\u73fe\u5728\u03b2-\u30e9\u30af\u30bf\u30de\u30fc\u30bc\u306f\u57fa\u8cea\u7279\u7570\u6027\u306e\u9055\u3044\u306b\u3088\u308a\u30da\u30cb\u30b7\u30ea\u30ca\u30fc\u30bc (\u30af\u30e9\u30b9A \u03b2-\u30e9\u30af\u30bf\u30de\u30fc\u30bc)\u30e1\u30bf\u30ed-\u03b2-\u30e9\u30af\u30bf\u30de\u30fc\u30bc (\u30af\u30e9\u30b9B \u03b2-\u30e9\u30af\u30bf\u30de\u30fc\u30bc\u3001\u4e9c\u925b-\u03b2-\u30e9\u30af\u30bf\u30de\u30fc\u30bc\u3001\u30ab\u30eb\u30d0\u30da\u30cd\u30de\u30fc\u30bc)\u30bb\u30d5\u30a1\u30ed\u30b9\u30dd\u30ea\u30ca\u30fc\u30bc (\u30af\u30e9\u30b9C \u03b2-\u30e9\u30af\u30bf\u30de\u30fc\u30bc)\u30aa\u30ad\u30b5\u30b7\u30ea\u30ca\u30fc\u30bc (\u30af\u30e9\u30b9D \u03b2-\u30e9\u30af\u30bf\u30de\u30fc\u30bc)\u304c\u5b58\u5728\u3059\u308b[1][2][3][4]\u3002\u3053\u308c\u30894\u7a2e\u306e\u03b2-\u30e9\u30af\u30bf\u30de\u30fc\u30bc\u306e\u3046\u3061\u3001\u30af\u30e9\u30b9B \u03b2-\u30e9\u30af\u30bf\u30de\u30fc\u30bc\u306f\u6d3b\u6027\u4e2d\u5fc3\u306b\u4e9c\u925b\u3092\u6301\u3064\u304c\u3001\u4ed6\u306f\u30bb\u30ea\u30f3\u6b8b\u57fa\u3092\u6301\u3064\u3002\u30da\u30cb\u30b7\u30ea\u30ca\u30fc\u30bc\u306f\u30da\u30cb\u30b7\u30ea\u30f3\u7cfb\u6297\u751f\u7269\u8cea\u3068\u7b2c\u4e8c\u4e16\u4ee3\u30bb\u30d5\u30a1\u30ed\u30b9\u30dd\u30ea\u30f3\u3092\u5206\u89e3\u3059\u308b\u306e\u306b\u5bfe\u3057\u3066\u3001\u30bb\u30d5\u30a1\u30ed\u30b9\u30dd\u30ea\u30ca\u30fc\u30bc\u306f\u4e3b\u306b\u30bb\u30d5\u30a1\u30ed\u30b9\u30dd\u30ea\u30f3\u3092\u5206\u89e3\u3059\u308b\u3002\u30aa\u30ad\u30b5\u30b7\u30ea\u30ca\u30fc\u30bc\u306f\u30aa\u30ad\u30b5\u30b7\u30ea\u30f3\u3092\u3082\u5206\u89e3\u3059\u308b\u30da\u30cb\u30b7\u30ea\u30ca\u30fc\u30bc\u3067\u3042\u308a\u3001\u30e1\u30bf\u30ed-\u03b2-\u30e9\u30af\u30bf\u30de\u30fc\u30bc\u306f\u30ab\u30eb\u30d0\u30da\u30cd\u30e0\u7cfb\u6297\u751f\u7269\u8cea\u3092\u5206\u89e3\u3059\u308b\u70b9\u306b\u7279\u5fb4\u304c\u3042\u308b\u3002\u03b2-\u30e9\u30af\u30bf\u30de\u30fc\u30bc\u306e\u907a\u4f1d\u5b50\u306f\u3001\u7d30\u83cc\u306e\u67d3\u8272\u4f53\u4e0a\u3042\u308b\u3044\u306f\u30d7\u30e9\u30b9\u30df\u30c9\u4e0a\u306b\u5b58\u5728\u3059\u308b\u3002\u7279\u306b\u4f1d\u9054\u6027\u85ac\u5264\u8010\u6027\u30d7\u30e9\u30b9\u30df\u30c9 (drug resistance plasmid\uff09\u306b\u5b58\u5728\u3059\u308b\u03b2-\u30e9\u30af\u30bf\u30de\u30fc\u30bc\u907a\u4f1d\u5b50\u306f\u83cc\u7a2e\u7279\u7570\u6027\u3082\u5c11\u306a\u304f\u591a\u5264\u8010\u6027\u83cc\u306e\u767a\u751f\u306b\u3082\u95a2\u4e0e\u3057\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u308b\u3002^ \u03b2-\u30e9\u30af\u30bf\u30e0\u8010\u6027\u83cc\u3068\u305d\u306e\u691c\u51fa\u65b9\u6cd5\u3001\u95a2\u6771\u5316\u5b66^ Bush, K. et. al. A functional classification scheme for \u03b2-lactamases and its correlation with molecular structure, Antimicrob Agents Chemother., 39, 1211-1233, 1995.^  Ambler, R. P., The structure of \u03b2-lactameses, Philos Trans R Society Lond (Biol), 289, 321-331, 1980.^ \u77f3\u4e95\u826f\u548c\u3001\u57fa\u8cea\u7279\u7570\u6027\u62e1\u5f35\u578b\u03b2-\u30e9\u30af\u30bf\u30de\u30fc\u30bc\u7523\u751f\u5927\u8178\u83cc\u3001\u30af\u30ec\u30d6\u30b7\u30a8\u30e9\u3001\u81e8\u5e8a\u3068\u5fae\u751f\u7269\u300126\u3001121-125, 1999.\u95a2\u9023\u9805\u76ee[\u7de8\u96c6]"},{"@context":"http:\/\/schema.org\/","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"https:\/\/wiki.edu.vn\/jp\/wiki3\/#breadcrumbitem","name":"Enzyklop\u00e4die"}},{"@type":"ListItem","position":2,"item":{"@id":"https:\/\/wiki.edu.vn\/jp\/wiki3\/archives\/7946#breadcrumbitem","name":"\u03b2-\u30e9\u30af\u30bf\u30de\u30fc\u30bc – Wikipedia"}}]}]