[{"@context":"http:\/\/schema.org\/","@type":"BlogPosting","@id":"https:\/\/wiki.edu.vn\/jp\/wiki6\/archives\/7069#BlogPosting","mainEntityOfPage":"https:\/\/wiki.edu.vn\/jp\/wiki6\/archives\/7069","headline":"\u30a4\u30df\u30ce\u7cd6 – Wikipedia","name":"\u30a4\u30df\u30ce\u7cd6 – Wikipedia","description":"\u30a4\u30df\u30ce\u7cd6\uff08\u30a4\u30df\u30ce\u3068\u3046\u3001\u82f1: Iminosugar\uff09\u306f\u3001\u74b0\u4e2d\u306e\u9178\u7d20\u539f\u5b50\u304c\u7a92\u7d20\u539f\u5b50\u306b\u7f6e\u304d\u63db\u308f\u3063\u305f\u69cb\u9020\u3092\u6301\u3064\u7cd6\u306e\u30a2\u30ca\u30ed\u30b0\u3067\u3042\u308b\u3002 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 \u30a4\u30df\u30ce\u7cd6\uff08\u30a4\u30df\u30ce\u3068\u3046\u3001\u82f1: Iminosugar\uff09\u306f\u3001\u74b0\u4e2d\u306e\u9178\u7d20\u539f\u5b50\u304c\u7a92\u7d20\u539f\u5b50\u306b\u7f6e\u304d\u63db\u308f\u3063\u305f\u69cb\u9020\u3092\u6301\u3064\u7cd6\u306e\u30a2\u30ca\u30ed\u30b0\u3067\u3042\u308b\u3002\u30a4\u30df\u30ce\u7cd6\u306f\u690d\u7269\u306b\u542b\u307e\u308c\u3001\u690d\u7269\u306e\u6301\u3064\u4e00\u90e8\u306e\u533b\u85ac\u54c1\u52b9\u679c\u306e\u539f\u56e0\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u308b[1]\u3002\u5929\u7136\u304b\u3089\u521d\u3081\u3066\u5358\u96e2\u3055\u308c\u305f\u30a4\u30df\u30ce\u7cd6\u306f\u3001\u30af\u30ef\u306b\u542b\u307e\u308c\u308b1-\u30c7\u30aa\u30ad\u30b7\u30ce\u30b8\u30ea\u30de\u30a4\u30b7\u30f3 (DNJ) \u3067\u30011976\u5e74\u306b\u5831\u544a\u3055\u308c\u305f\u304c\u3001\u305d\u306e\u5f8c\u6570\u5e74\u9593\u306f\u4ed6\u306b\u307b\u3068\u3093\u3069\u767a\u898b\u3055\u308c\u306a\u304b\u3063\u305f[2]\u3002\u751f\u5316\u5b66\u7684\u6d3b\u6027\u306e\u9762\u3067\u306f\u3001DNJ\u3084\u521d\u671f\u306b\u767a\u898b\u3055\u308c\u305f\u30a4\u30df\u30ce\u7cd6\u306e\u4ed6\u306e\u4f8b\u3067\u3042\u308b1,4-\u30b8\u30c7\u30aa\u30ad\u30b7-1,4-\u30a4\u30df\u30ce-D-\u30a2\u30e9\u30d3\u30cb\u30c8\u30fc\u30eb (DAB) \u306f\u3001\u03b1-\u30b0\u30eb\u30b3\u30b7\u30c0\u30fc\u30bc\u963b\u5bb3\u5264\u3068\u3057\u3066\u4f5c\u7528\u3057\u3001\u6297\u7cd6\u5c3f\u75c5\u85ac\u3001\u6297\u30a6\u30a4\u30eb\u30b9\u85ac\u306e\u6027\u8cea\u3092\u6301\u3064\u3002DNJ\u304b\u3089\u4f5c\u3089\u308c\u305f2\u7a2e\u985e\u306e\u8a98\u5c0e\u4f53\u304c\u73fe\u5728\u3082\u7528\u3044\u3089\u308c\u3066\u3044\u308b\u3002N-\u30d2\u30c9\u30ed\u30ad\u30b7\u30a8\u30c1\u30eb-DNJ\uff08\u30df\u30b0\u30ea\u30c8\u30fc\u30eb\uff09\u306f\u7cd6\u5c3f\u75c5\u3001N-\u30d6\u30c1\u30eb-DNJ\uff08\u30df\u30b0\u30eb\u30b9\u30bf\u30c3\u30c8\uff09\u306f\u30b4\u30fc\u30b7\u30a7\u75c5\u306e\u6cbb\u7642\u306b\u7528\u3044\u3089\u308c\u3066\u3044\u308b\u30021980\u5e74\u4ee3\u306b\u306f\u3001\u30de\u30f3\u30ce\u30fc\u30b9\u30a2\u30ca\u30ed\u30b0\u306e\u30b9\u30ef\u30a4\u30f3\u30bd\u30cb\u30f3\u3084\u30b0\u30eb\u30b3\u30fc\u30b9\u30a2\u30ca\u30ed\u30b0\u306e\u30ab\u30b9\u30bf\u30ce\u30b9\u30da\u30eb\u30df\u30f3\u3067\u3001\u6297\u764c\u6d3b\u6027\u3084\u6297\u30a6\u30a4\u30eb\u30b9\u6d3b\u6027\u304c\u767a\u898b\u3055\u308c\u305f[3]\u3002\u73fe\u5728\u3001\u690d\u7269\u3084\u5fae\u751f\u7269\u4e2d\u304b\u3089200\u7a2e\u985e\u4ee5\u4e0a\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u3002\u521d\u671f\u306e\u3082\u306e\u306e\u751f\u7269\u5b66\u6d3b\u6027\u306f\u30b0\u30ea\u30b3\u30b7\u30c0\u30fc\u30bc\u963b\u5bb3\u4f5c\u7528\u306b\u7531\u6765\u3057\u3066\u3044\u305f\u304c\u3001\u6700\u8fd1\u306f\u3001\u7cd6\u53d7\u5bb9\u4f53\u3084\u3001\u30e9\u30a4\u30bd\u30be\u30fc\u30e0\u75c5\u3084\u56a2\u80de\u6027\u7dda\u7dad\u75c7\u7b49\u306e\u30b7\u30e3\u30da\u30ed\u30f3\u6b20\u640d\u9175\u7d20\u3068\u95a2\u9023\u3059\u308b\u3082\u306e\u304c\u5897\u3048\u3066\u304d\u3066\u3044\u308b[2]\u3002\u69cb\u9020\u3068\u5b89\u5b9a\u6027[\u7de8\u96c6]\u30a4\u30df\u30ce\u7cd6\u306e\u74b0\u306e\u7a92\u7d20\u539f\u5b50\u306f\u30d8\u30df\u30a2\u30df\u30ca\u30fc\u30eb\u7d50\u5408\u3092\u6301\u3061\u3001\u901a\u5e38\u306e\u914d\u7cd6\u4f53\u306e\u30d8\u30df\u30a2\u30bb\u30bf\u30fc\u30eb\u306e\u3088\u3046\u306b\u4e0d\u5b89\u5b9a\u3067\u3042\u308b\u3002\u30a4\u30df\u30ce\u7cd6\u306e1-\u30c7\u30aa\u30ad\u30b7\u30a2\u30ca\u30ed\u30b0\u306fC-\u30b0\u30ea\u30b3\u30b7\u30c9\u3067\u3042\u308a\u3001\u7a92\u7d20\u539f\u5b50\u306f\u30a2\u30df\u30f3\u7d50\u5408\u306e\u4e00\u90e8\u3068\u306a\u308b\u3002\u3053\u308c\u3089\u306e\u30d4\u30da\u30ea\u30b8\u30f3\u3001\u30d4\u30ed\u30ea\u30b8\u30f3\u3084\u4f3c\u305f\u3088\u3046\u306a\u74b0\u306f\u5b89\u5b9a\u3067\u3042\u308b[4]\u3002^ Watson AA, Fleet GW, Asano N, Molyneux RJ, Nash RJ (2001). \u201cPolyhydroxylated alkaloids\u2014natural occurrence and therapeutic applications\u201d. Phytochemistry 56 (3):  265\u201395. doi:10.1016\/S0031-9422(00)00451-9. PMID\u00a011243453.\u00a0^ a b Nash RJ, Kato A, Yu CY, Fleet GW (2011). \u201cIminosugars as therapeutic agents: recent advances and promising trends\u201d. Future Med Chem 3 (12):  1513\u201321. doi:10.4155\/fmc.11.117. PMID\u00a021882944.\u00a0^ Asano N, Nash RJ, Molyneux RJ, Fleet GW (2000). \u201cNitrogen-in-the-Ring Sugar Mimetics: Natural Occurrence, Biological Activity and Prospects for Therapeutic Application\u201d. Tetrahedron Asymmetry 11:  1645-1680. doi:10.1016\/S0957-4166(00)00113-0.\u00a0^ Compain P, Chagnault V, Martin OR (2009). \u201cTactics and strategies for the synthesis of iminosugar C-glycosides: a review\u201d. Tetrahedron: Asymmetry 20:  672\u2013711. doi:10.1016\/j.tetasy.2009.03.031.\u00a0\u95a2\u9023\u9805\u76ee[\u7de8\u96c6]"},{"@context":"http:\/\/schema.org\/","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"https:\/\/wiki.edu.vn\/jp\/wiki6\/#breadcrumbitem","name":"Enzyklop\u00e4die"}},{"@type":"ListItem","position":2,"item":{"@id":"https:\/\/wiki.edu.vn\/jp\/wiki6\/archives\/7069#breadcrumbitem","name":"\u30a4\u30df\u30ce\u7cd6 – Wikipedia"}}]}]